Anca Zgură, Laurenţia Galeş, Prof. Breast, ovarian, and cervical cancer are the most common cancers diagnosed during pregnancy.
You are on page 1of 3 Search inside document The human colon, or large intestine, is a muscular, tube-shaped organ measuring about 4 feet long. It extends from the end of the small bowel to the rectum; some doctors may include the rectum as the end of the colon. The term colorectal describes this area that begins at the colon and ends at the anus. Typically, the first or right portion of the colon which is called the ascending colon moves up from the lower right portion of the abdomen.
The manifestations encountered in colorectal cancer, rectal cancer with no bleeding as abdominal pain, constipation, vomiting, nausea, rectal bleeding and altered bowel movements, are also found in normal pregnancy.
In this paper, we present a case of colorectal cancer with hepatic metastasis diagnosed in a year-old preganant woman IIG, 1Pat 32 weeks of pregnancy. Keywords pregnancy, colorectal cancer, metastasis, teratogencity, chemotherapy Rezumat Incidenţa cancerului colorectal în timpul sarcinii este mică, de un caz la 1.
Cancerul mamar, ovarian şi cel cervical sunt cele mai frecvente tipuri de cancer diagnosticate în timpul sarcinii. Manifestările întâlnite în cancerul colorectal, precum dureri abdominale, constipaţie, vărsături, greaţă, sângerări rectale şi tulburări intestinale, se întâlnesc şi în timpul sarcinii normale, făcând dificilă diagnosticarea pe parcursul sarcinii.
În această lucrare vă prezentăm cazul unei paciente de 36 de ani IIG, 1Pîn săptămâna a a de sarcină, diagnosticată cu cancer colorectal, prezentând rectal cancer with no bleeding metastaze hepatice. Cuvinte cheie cancer colorectal metastaze teratogenitate chimioterapie Introduction The incidence of colorectal cancer during rectal cancer with no bleeding is reduced, being estimated at approximately one in every preganancies Breast, ovarian and cervical cancer are the most common cancers rectal cancer with no bleeding during pregnancy 2.
The manifestations encountered in colorectal cancer, such as abdominal pain, constipation, vomiting, nausea, rectal bleeding and altered bowel movements, are also found in normal pregnancy 5. Most of the colorectal cancers are missed and are diagnosed in advanced stages. Using the antineoplastic agents in a pregnant patient is a difficult decision, with many of safety and efficacy implications 6.
The treatment plan depends on the desire of the pregnant woman, the stage of the disease, the possible teratogenic effects of the antineoplastic agents and abortion We present parazitii intestinali la adulti simptome this paper a case of colorectal cancer with hepatic metastasis diagnosed in a patient at 32 weeks of pregnancy.
Figure 1. Laryngeal papillomas genital warts also had constipation and anemia. She was initially evaluated by her gynecologist, who suggested a second opinion from a gastroenterologist, who performed an abdominal and pelvic IRM. The abdominal and pelvic Rectal cancer with no bleeding evaluation revealed global hepatomegaly mm cranio caudal right lobe, 97 rectal cancer with no bleeding antero-posterior left lobeand more lobular contour space replacement formation.
The CT scan of the thorax was without secondary pulmonary determinations. There was no family history of cancer. The physical examination at the time was unremarkable, except for normal signs of pregnancy. The patient was anemic at the time of presentation, the hemoglobin level was 9. After the imagistic and biological evaluation, she was refered to a surgeon, who thought that her pregnancy would make difficult to receive prompt adjuvant therapy. The patient was only week pregnant at the time of diagnosis.
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A caesarean section was performed, resulting in the birth of a premature baby, weighing g, who received an Apgar score of 9. During the same operation, a left hemicolectomy and right oophorectomy were also performed.
The histopatological raport revealed a moderate adenocarcinoma G2six nodes were examinated, but only two were positive. The histopatological examination of the ovary showed metastasis of moderate adenocarcinoma Krukenberg ovary.
Before deciding on the initiation of chemotherapy, the patient experienced altered generalized status, medium ascites, pleurisy and gambling edema. She received a cycle of adjuvant chemotherapy consisting of cetuximab mg.
Rectal cancer with no bleeding patient rectal cancer with no bleeding the therapy with supportive treatment and minimal hematologic and non-hematologic toxicities. After one month, we changed the chemotheray cycle with cetuximab, oxaliplatin and 5-FU, due to the improvement of rectal cancer with no bleeding general state.
A follow-up CT scan after three months showed evolution in mild numerical regression of liver lesions.
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The hepatomegaly was maintained. Fine fluid blade in dimensional regression. Without bone metastases. The adjuvant chemotherapy combined with targeted therapy using cetuximab has been considered for the patient in order to eradicate the metastatic disease.
Discussion Despite the low incidence rate of 0. Colorectal cancer is among the eight most common malignancies in pregnancy 2. Colorectal cancer in pregnancy represents a serious situation, and there are many challenging issues regarding the diagnosis and management in pregnancy. Because the signs and simptoms are similar in pregnancy and colorectal cancer, the colorectal cancer can be concealed In our patient, the abdominal pain was misdiagnosed as a sign and simptom of a normal pregnancy.
There are limitations and contraindications for using imaging tests during pregnancy. IRM remains relatively safe in pregnancy and the best option to evaluate the colorectal cancer. Serum CEA is an important test used in the evaluation of patients with colorectal cancer CEA levels during pregnancy may be rectal cancer with no bleeding and can be used for monitoring the response of the treatment 15, Due to the fact that colorectal cancer is encoutered in the eldery and rarerly in young patients, it is assumed that there are a number of predisposing factors, such as Lynch syndrome, Peutz-Jeghers syndrome and inflammatory bowel disease Another challenging issue is the treatment, which should be started as early for rectal cancer with no bleeding mother, and is based on the gestational age and tumor stage.
If diagnosis occurs during the first trimester of pregnancy, it may be expected until the fetus becomes viable, but with significant tumor progression 18, If the diagnosis occurs after the 20th week of pregnancy, colon resection may be delayed. Chemotheray is safer in rectal cancer with no bleeding second and third trimesters, when organogenesis is complete There are no human data for the effect of cetuximab in pregnancy The ovarian metastatic disease from colorectal cancer is another challenge.
The incidence of ovarian metastases from colorectal cancer is higher in pregnant women. The survival of the pregnant woman familial cancer program uvm ovarian metastases is poor. Nesbitt et al. There are no rectal cancer with no bleeding risk due to the malignancy itself, even in metastasis cases. The pregnant woman with colorectal cancer has a poor prognosis.
A review of 15 cases revealed that all patients with colorectal cancer presented in stage IV, and these patients died in 12 months after delivery Conclusions Colorectal cancer in pregnancy represents a diagnostic and therapeutic challenge.
Because the signs and simptoms are similar in pregnancy and colorectal cancer, the diagnosis of colorectal cancer is often delayed. The therapeutic decison for a enterobius vermicularis sintomi patient with colorectal cancer should involve a multidisciplinary team, and there must be taken into account the life of the unborn child and the survival of the mother.
Conflict of interests: The authors declare no conflict of interests.
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Distribuie pe: DESCRIERE This fourth edition of Surgery of the Anus, Rectum and Colon continues to redefine the field, with its comprehensive coverage of common and rare colorectal conditions, advances in the molecular biology and genetics of colorectal diseases, and new laparoscopic techniques. Contributions from international experts on specialized topics and various new illustrations ensure that the extensive text is not only current and authoritative, but easy to understand.
Cappell MS. Gastrointestinal endoscopy in high-risk patients. Dig Dis. Brent RL.
Cancerul colorectal în sarcină
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