Selected References These references are in PubMed.
This may not be the complete list of references from this article. Oxygen activation by cytochrome P Annu Rev Biochem.
Hereditary Colorectal Cancer: Laura Valle · | Books Express
The molecular biology of cytochrome Ps. Pharmacol Rev.
Cancer biology part 5 Genes associated with cancer
The P superfamily: update on new sequences, gene mapping, and recommended nomenclature. DNA Cell Biol.
Evolution of cytochrome P proteins. Mol Biol Evol. Evolution of the P gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation. Trends Genet. Oxidation of toxic and carcinogenic chemicals by human cytochrome P enzymes.
Chem Res Toxicol. Constitutive and inducible expression of human cytochrome PIA1 in yeast Saccharomyces cerevisiae: an alternative enzyme source for in vitro studies. Biochem Biophys Res Commun. The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes.
- Cancerul – de la etiologie la abordări terapeutice
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- Negreş Simona, As.
J Pharmacol Exp Ther. Expression of a human liver cytochrome P protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae. Mol Pharmacol.
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism. Identification of a new variant CYP2D6 allele lacking the codon encoding Lys possible association with the poor metabolizer phenotype.
A tobacco smoke-derived nitrosamine, 4- methylnitrosamino 3-pyridyl butanone, is activated by multiple human cytochrome Ps including the polymorphic human cytochrome PD6.
Mutagenic activation of 2-aminomethylimidazo[4,5-f]quinoline by complementary DNA-expressed human liver P Cancer Res. J Biol Chem. Carcinogenicity of mutagenic heterocyclic amines formed during the cooking process. Mutat Res.
Induction of hepatocellular carcinoma in nonhuman primates by chemical carcinogens. Cancer Detect Prev.
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Five of 12 forms of gemoderivate pentru oxiuri virus-expressed human hepatic cytochrome P metabolically activate aflatoxin B1. Assay for gene mutation in a human lymphoblast line, AHH-1, competent for xenobiotic metabolism.
A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing. Molecular genetics of the debrisoquin-sparteine polymorphism.
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Clin Pharmacol Ther. Relevance of metabolic polymorphisms to human cancer genetic and environmental factors evaluation of epidemiologic evidence.
Identification of a human liver cytochrome P homologous to the major isosafrole-inducible cytochrome P in the rat. Purification cancer genetic and environmental factors characterization of the human liver cytochromes P involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism.
Identification and quantitation in human liver of cytochromes P analogous to rabbit cytochromes P forms cancer genetic and environmental factors and 6. Metabolism of N-nitrosodialkylamines by human liver microsomes.