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Department of Ophthalmology, Grigore T.

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E-mail: moc. We report the detection of HPV papillomavirus journal in papillomavirus journal sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.

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The method used for the detection of HPV was real time polymerase chain reaction. The evolution was favorable after surgical removal of the tumor and the patient papillomavirus journal explained that papillomavirus journal follow-up is essential to avoid recurrence. Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.

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The association between HPV papillomavirus journal and eye tumors is little explored territory. Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in papillomavirus journal susceptible cells.

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Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and papillomavirus journal in June The year-old patient presented at papillomavirus journal Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half. He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist.

The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture papillomavirus journal using sunglasses.

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All other ophthalmological findings were normal. Conjunctival papillomavirus journal was performed before surgery, and no bacterial infection was found.

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The CT scan of the head papillomavirus journal neck showed no signs of tumor invasion of the papillomavirus journal or the lymph nodes.

The limbic lesion was removed surgically with 2 papillomavirus journal margin of normal tissue and diathermy of the adjacent sclera was done. At the end, the remaining temporal defect was restored using papillomavirus journal supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Papillomavirus journal polymerase chain reaction PCR papillomavirus journal and refrigerated at 4°C until processing.

Papillomavirus journal exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.