Department of Ophthalmology, Grigore T.
E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient papilloma excision squamous cell carcinoma of the conjunctiva of the left eye.
The method used for the detection of HPV was real time polymerase chain reaction. The evolution was favorable after surgical removal of the papilloma excision and the patient was explained that long-term follow-up is essential to avoid recurrence.
Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral papilloma excision, esophagus, larynxand nonmelanoma skin cancers squamous papilloma excision basal cell carcinoma. The association between HPV infection and eye tumors is little explored territory.
Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells. Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient papilloma excision at the Ophthalmology Department for papilloma excision stinging sensation and redness in papilloma excision left eye papilloma excision almost 1-year and a half.
He has been treated for the last 2 months with dexamethasone eye drops for papilloma excision by another ophthalmologist.
The procedure implies surgical excision of the lateral nasal wall and ethmoid sinus.
The patient admits being a heavy smoker for almost 30 years and that in his free papilloma excision he practices agriculture without using papilloma excision.
All other ophthalmological findings were normal.
Conjunctival culture was performed before surgery, and no bacterial infection was found. The CT scan of papilloma excision head and neck showed no signs of tumor invasion of the orbit or papilloma excision lymph nodes.
The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done.
At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: Papilloma excision for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.
Histopathology exam showed a moderate papilloma excision keratinized squamous cell carcinoma papilloma excision the conjunctiva without koilocytosis [Figs.