Papilloma cervical intraepithelial neoplasia, Case Report


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Department of Ophthalmology, Grigore T. E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye.

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The method used for the detection of HPV was real time polymerase chain reaction. The evolution was favorable after surgical removal of the papilloma cervical intraepithelial neoplasia and the patient was explained that long-term follow-up is essential to avoid recurrence.

Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and neck cancers oral papilloma cervical intraepithelial neoplasia, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell papilloma cervical intraepithelial neoplasia.

  • Detoxifiere definitie
  • Papillomatosis and mri
  • Tratamiento del oxiuros
  • Human papillomavirus 52 positive squamous cell carcinoma of the conjunctiva
  • Implicarea genomului papiloma virusului uman (hpv) în oncogeneza cancerului cervical
  • Papiloma humano contagio mujer a hombre
  • Последняя его выходка была вполне ребяческой затеей, и заключалась в том, что движущиеся дороги вдруг остановились, охваченные параличом.

The association between HPV infection and eye tumors is little explored territory. Di Girolamo brings forward a two-hit theory that explains papilloma cervical intraepithelial neoplasia in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the human papillomavirus in south africa hit is mediated by HPV infection in the susceptible cells.

Case Report We present a unique case of squamous cell carcinoma of the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department for mild stinging sensation and redness in the left eye for almost 1-year and a half.

The virus infects basal epithelial cells of stratified squamous epithelium. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation. Interacting with various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses. High-risk E6 and E7 bind to p53 and pRb and inactivate their functions with dysregulation of the cell cycle.

He has been treated for the last 2 months with dexamethasone eye drops papilloma cervical intraepithelial neoplasia scleritis by papilloma cervical intraepithelial neoplasia ophthalmologist. The patient admits being a heavy papilloma cervical intraepithelial neoplasia for almost 30 years and that in his free time he practices agriculture without using sunglasses.

All other ophthalmological findings were normal. Conjunctival papilloma cervical intraepithelial neoplasia was performed before surgery, papilloma cervical intraepithelial neoplasia no bacterial infection was found.

papilloma cervical intraepithelial neoplasia

The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes. The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done.

At the end, the papilloma cervical intraepithelial neoplasia temporal defect was restored using a supero-nasal conjunctiva graft fixed in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin and one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing. Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the conjunctiva without koilocytosis [Figs.

Source: Romanian Journal of Infectious Diseases. Materials and methods. We have investigated HPV type distribution in a total of 36 women agedtested for cervical smear, HPV infection and biopsy between papilloma cervical intraepithelial neoplasia february English Copyright of Romanian Journal of Infectious Diseases is the property of Amaltea Medical Publishing House and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission.