Abstract Aim: to describe two cases of familial papillary thyroid carcinoma.
Material and methods: patients were investigated by fine needle biopsy, MRI imaging and tumor biopsy, first case and histological examination of colonic and papillary thyroid carcinoma variant follicular tumors first case and histological examination of thyroid tumor second case. Results papillary thyroid carcinoma variant follicular discussion: case presentation: first case, 68 years old man had a colonic polyposis attenuated form with only a few polyps and a thyroid nodule.
After hemicolectomy papillary thyroid carcinoma variant follicular a supposed colonic carcinoma with liver and lung metastases, histological examination revealed no malignant colonic disease. Two month later the diagnosis of invasive thyroid tumor with lymph node metastases was made, but only an open biopsy was done because tumor invasiveness demonstrated on MTI imaging.
The biopsy identified papillary thyroid carcinoma variant follicular papillary thyroid carcinoma. Case 2: the son of the patient 30 years old without known diseases was invited to be assessed for thyroid disease.
Ultrasound examination discovered a large nodule with microcalcifications. Microscopic examination done after total thyroidectomy revealed a cribriform morular variant of papillary thyroid carcinoma, a variant that is known to be associated with FAP.
Înțelesul "papillary" în dicționarul Engleză
Radioiodine ablation was made followed by suppressive thyroxine treatment. Papillary thyroid carcinoma variant follicular the second case adenomatous polyposis was not found yet. In our knowledge these are the first cases of familial thyroid papillary carcinomas in our setting.
Papillary Thyroid Carcinoma
Familial history allowed an earlier diagnosis and a good management of the disease in the second case. Conclusions: according to the literature and our first experience, screening for thyroid cancer must be done in all patients with FAP and in those with a FAP proband in the family.
Sinonimele și antonimele papillary în dicționarul de sinonime Engleză
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Cancerul cu celule Hurthle este foarte rar și potențial cea mai agresivă formă de cancer tiroidian folicular. Carcinom papilar Carcinom folicular Carcinom slab difereniat Carcinom. Diferenţe între codurile morfologice din ediţiile a doua ºi a treia. Cu toate acestea, pacienţii cu exces de calcitonină cum sunt cei cu carcinom tiroidian medular au. Epiteliul folicular este înalt, coloidul este în cantitate mică.
Ito Y, Miyauchi A, Ishikawa H, et al: Our experience of treatment of cribriform morular variant of papillary thyroid carcinoma; difference in clinicopathological features of FAP-associated and sporadic patients. Mc Donald TJ.
Carcinom folicular vs adenomatos
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Reprezinta cresterea de volum a glandei tiroide, prin prezenta unor noduli, unici sau multipli, pastrand un nivel normal de hormoni tiroidieni.