Ovarian cancer mucinous, Studiu clinico-patologic al tumorilor ovariene - experienţa de un an într-un centru medical


The aim of this study is a retrospective analysis of the spectrum of ovarian tumors: statistics, epidemiology and pathological features, based on one-year experience in our hospital. Materials and method. We analyzed 58 cases registered in the Pathology Department as oophorectomy or hysterectomy ovarian cancer mucinous diagnosed with ovarian tumors, including benign, borderline and malignant tumors of various histological types.

Based on their tumoral behavior, we had: three cases of benign tumors, all of them associated with a different histological tumor type and grade in the contralateral ovary, 12 cases of borderline tumors ovarian cancer mucinous 46 cases of malignant tumors ovarian cancer mucinous cases of primary and 7 cases of secondary tumors. The most frequent histologic type was represented by high-grade serous carcinoma Rare primary ovarian tumors were represented by: adult granulosa cell tumor, clear cell carcinoma, ovarian cancer mucinous serous-mucinous carcinoma and undifferentiated pleomorphic sarcoma 1.

The earliest age of all patients with ovarian tumors ovarian cancer mucinous 31 years old for the mixed serous-mucinous carcinoma. Mean age distribution was 52 years old for benign tumors, 51 ovarian cancer mucinous old for borderline and 60 years old for malignant tumors.

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Primary malignant tumors are the most frequent type of ovarian tumors and their age incidence ranges from the third to the eighth decade. The majority of secondary ovarian tumors are of endometrial origin.

Keywords ovarian tumors, benign, borderline, malignant Rezumat Obiectiv.

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Scopul acestui studiu este analiza retrospectivă a spectrului de tumori ovariene, din punct de vedere sta­tis­tic, epidemiologic şi al caracteristicilor histopatologice, re­pre­zen­tând experienţa de un an în spitalul nostru Ma­te­ria­le şi metodă.

Am ovarian cancer mucinous 58 de cazuri, din De­par­ta­­mentul de Anatomie Patologică, înregistrate ca piese de ooforectomie sau histerectomie diagnosticate cu tumori ovariene, cuprinzând diferite tipuri histologice de tumori ovariene benigne, borderline şi maligne.

Studiu clinico-patologic al tumorilor ovariene - experienţa de un an într-un centru medical

În funţie ovarian cancer mucinous caracterul tumoral, am identificat: trei cazuri de tumori benigne, toate asociate cu un alt tip histologic tu­moral în ovarul contralateral, 12 cazuri de tumori bor­der­line şi 46 de cazuri de tumori maligne dintre care 39 de cazuri de tumori primare şi 7 cazuri reprezentând tumori secundare.

Vârsta minimă în rândul tuturor pacientelor cu tumori ovariene a fost 31 de ani. Vârsta medie pe categorii a fost 52 de ani pentru tumori benigne, 51 de ani pentru tumori borderline şi 60 de ani pentru tumori maligne.

Tumorile maligne primare reprezintă cel ovarian cancer mucinous frecvent tip de tumori ovariene, cu o incidenţă de vârstă cuprinsă între decadele a treia şi a opta de viaţă. Majoritatea tumorilor ovariene secundare sunt de origine endometrială.

ovarian cancer mucinous

The relative frequency­ of ovarian tumor is different for western and Asian countries. Two third of ovarian tumors occur in women of reproductive age group 1.

Histopathology Ovary--Borderline ovarian tumor

Borderline tumors occur at slightly papillary thyroid carcinoma treatment options ages and malignant tumors are more common in women between 45 and 65 years old 2. Ovarian cancer represents the fifth cause of cancer and the fifth cause of death due to cancer in females in ovarian cancer mucinous European Union 3.

There are three major histologic subtypes ovarian cancer mucinous surface epithelial tumors: serous, mucinous and endometrioid. Serous carcinomas are divided in: high-grade serous carcinoma and low-grade serous carcinoma.

These tumors are associated with KRAS ovarian cancer mucinous mainly, and smoking is a risk factor, not associated with serous tumors. Mucinos tumors are composed of gastrointestinal type cell containing intracytoplasmic mucin and therefore, malignant tumors should always be carefully examined for excluding metastatic tumors with similar morphology 2,5. Endometrioid tumors of the ovary are similar to endometrioid tumors of the endometrium.

  • Que es examen oxiuros
  • Granulosa cell tumors of the ovary: prognostic factors and outcome.
  • MUCINOUS - Definiția și sinonimele mucinous în dicționarul Engleză
  • Material and method: The study has included women diagnosed with ovarian cancer.
  • Apasă pentru a vedea definiția originală «mucinous» în dicționarul Engleză dictionary.

Other rare epithelial tumors include: clear cell tumors, Brenner tumors, mixed serous-mucinous or mixed epithelial-mesenchymal tumors. The group includes: teratomas mature, immature and monodermal or highly specializeddysgerminoma, Yolk-sac tumor, non-gestational chorio-carcinoma, embryonal carcinoma and mixed tumors.

In this group, only mature teratomas and monodermal teratoma - benign struma ovarii are benign tumors.

Înțelesul "mucinous" în dicționarul Engleză

Sex-cord stromal tumors include neoplasms that contain granulosa cells, theca cells, fibloblasts, Sertoli cells and Leydig cells, which are derived from ovarian­ stroma, that is formed from sex cords under the influences of coelomic and mesonephric epithelium. This type of tumor has clinical importance because of its potential to elaborate ovarian cancer mucinous amounts of estrogens and because it has malignant potential.

Ovarian cancer mucinous fibromas are hormonally inactive; Sertoli and Leydig cell tumors are active and have masculinizing or de-fe­mi­nization effects 5,7. Metastases derived from non-gynecological sites are eleven times more frequent than those derived from female genital organs, the gastrointestinal tract being the ovarian cancer mucinous common origin 7.

ovarian cancer mucinous

Traducerea «mucinous» în 25 de limbi

Tumors from the stomach, colon, and breast are the three most common neoplasms that metastasize to the ovary 8. Materials and method We performed a retrospective analysis of ovarian tumor cases registered at the Pathology Department of the Bucharest Emergency University Ovarian cancer mucinous for a period of one year.

The study included 58 cases of oophorectomy, salpingo-oophorectomy or hysterectomy specimens diagnosed with benign, borderline or malignant tumors of various histologic types.

We classified them according to their morphologic features, we analyzed the age distribution for each category, the clinical manifestations, regional papilloma tumors, lymph nodes status, peritoneal involvement or metastases in available cases; the follow-up was possible in a ovarian cancer mucinous number of cases.

All data was obtained from medical records and from the Statistics Department of University Emergency Hospital in Bucharest.

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Results and discussions Based on their tumoral behavior, we had Figure 1 : three cases 4. In our study we found a smaller prevalence of benign tumors of only 4. Figure 1.

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The distribution of ovarian tumors over a period of one year The most frequent histologic type among all ovarian tumors was represented by high-grade serous carcinoma Mucinous carcinoma accounted for Studies of molecular alteration ovarian cancer mucinous suggested that this tumors do actually progress from endometriosis 4, We had one case of poorly differentiated carcinoma of unknown ovarian cancer mucinous.

All the metastasis cases were large excision specimens and were integrated in the clinico-pathological context. The gynecological origin is usually less frequent than the gastrointestinal origin, which is the first cause of ovarian cancer mucinous metastasis 7,8, Rare primary ovarian tumors were represented by: adult granulosa cell tumor Figure ovarian cancer mucinous cell carcinoma, mixed serous-mucinous carcinoma, and undifferentiated pleomorphic sarcoma 1.

Figure 2.

Studiu clinico-patologic al tumorilor ovariene - experienţa de un an într-un centru medical

Intraoperative Amacroscopic B and microscopic C aspect of a voluminous left ovarian cyst in a patient of 60 years old; after the histopathological analysis the diagnose was adult granulosa cell tumor - note the micro-follicular pattern The earliest age of a patient with ovarian tumor was 31 years old for the mixed serous-mucinous carcinoma, a younger age than mean age for this type of tumor, but cases of patients within 16 to ovarian cancer mucinous years had been previously reported 13, Mean age distribution ovarian cancer mucinous ovarian cancer mucinous years old for benign tumors, with a range of 45 to 67 years old; 51 years old for borderline tumors, with a range of 32 to 73 years old; 60 years old for malignant tumors, with a range of 31 to 83 years old Figure 3.

Mean age distribution in the category of malignant tumors is shown in Figure 4. We found a higher age range for benign tumors, but considering the fact that they were associated with borderline tumors, we found it acceptable 2,4.

Figure 3.