Department of Ophthalmology, Grigore T.
E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye. The method used for the detection of HPV was real time polymerase chain reaction.
The evolution was favorable after surgical removal of the tumor and the patient was explained that long-term follow-up is essential to avoid recurrence. Keywords: Conjunctiva, eye, human papillomavirus 52, real time polymerase chain reaction, squamous cell carcinoma Human papillomavirus HPV infection is strongly associated with anogenital tumors cervix, penis, vulva, vagina, anushead and laryngeal papilloma treatment cancers oral cavity, esophagus, larynxand nonmelanoma skin cancers squamous and basal cell carcinoma.
The association between HPV laryngeal papilloma treatment and eye tumors is little explored territory. Di Girolamo brings forward a two-hit theory that explains cancerogenesis in OSSN: The first hit is mediated by ultraviolet radiation exposure that causes genetic alteration and the second hit is mediated by HPV infection in the susceptible cells.
Case Report We present a unique case simptome cancer de col squamous cell carcinoma laryngeal papilloma treatment the conjunctiva examined and treated in June The year-old patient presented at the Ophthalmology Department laryngeal papilloma treatment laryngeal papilloma treatment stinging sensation and redness in the left eye for almost 1-year and a half.
He has been treated for the last 2 months with dexamethasone eye drops for scleritis by another ophthalmologist.
Papilomatoza laringiană. Chișinău: CEP Medicina, laryngeal papilloma treatment, vol. Abstract: Laryngeal papillomatosis is a disease consisting of tumors that grow inside the larynx voice boxvocal cords, or the air passages leading from the nose into the lungs respiratory tract. Laryngeal papillomatosis affects infants and small children as well as adults.
The patient admits being a heavy smoker for almost 30 years and that in his free time he practices agriculture without using sunglasses. All other ophthalmological findings were normal. Conjunctival culture was performed before surgery, and no bacterial infection was found.
The lack of a curative treatment and the tendency of the papillomatosis to recur in an extensive manner require an aggressive treatment. Although multiple medical therapies are available, their results are not always the desired ones. That is why nowadays the focus of laryngeal papilloma treatment therapy is on the surgical approach. The best results may be obtained thru multiple surgeries, with resection of all papilloma foci. Although this approach may impact the quality of life of the patients due to the multiple interventions required, the overall result translates into a physiologic airway.
The CT scan of the head and neck showed no signs of tumor invasion of the orbit or the lymph nodes. The limbic lesion was removed surgically with 2 mm margin of normal tissue and diathermy of the adjacent sclera was done. At the end, the remaining temporal defect was restored using a supero-nasal conjunctiva graft laryngeal papilloma treatment in position with interrupted and surjet The excised tumor was cut into 2 fragments: One for pathology preserved in formalin laryngeal papilloma treatment one for HPV genotyping preserved in Cobas polymerase chain reaction PCR solution and refrigerated at 4°C until processing.
The juvenile laryngeal papillomatosis is the most laryngeal papilloma treatment benign tumour of the larynx. In Sir Morrel MacKenzie describes papillomas as pharyngo-laryngeal lesions at a child, and the term of juvenile laryngeal papillomatosis has been introduced by Chevalier Jakson in The etiological agent is HPV types 6 and 11 and the section of the respiratory tract the most frequently infected is the squamocolumelar junction. Juvenile laryngeal papillomatosis is a disease more frequent between 3 and 5 years, characterised by multiple relapses and exuberant growth at the level of the laryngeal mucosa. The annual costs of the laryngeal papilloma treatment of this disease are over million USD.
Histopathology exam showed a moderate differentiated keratinized squamous cell carcinoma of the laryngeal papilloma treatment without koilocytosis [Figs.